EFFECTIVENESS OF NEURODEVELOPMENTAL THERAPY ON MOTOR FUNCTION IMPROVEMENT IN CHILDREN WITH SPASTIC CEREBRAL PALSY

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Sohaila Sohu
Sumera Makhdoom
Iqbal Ahmad Azhar
Sahaab Alvi
Duaa Joyo
Ayesha Khalid
Abdul Aziz

Abstract

Background: Spastic cerebral palsy is the most prevalent form of cerebral palsy in children, often leading to significant motor dysfunction and reduced functional independence. Neurodevelopmental therapy (NDT), based on the Bobath concept, is widely used in pediatric rehabilitation, yet evidence regarding its effectiveness remains varied.


Objective: To assess the impact of neurodevelopmental therapy on motor function and functional mobility in children with spastic cerebral palsy.


Methods: A randomized controlled trial was conducted over four months in South Punjab, including 60 children with spastic cerebral palsy (GMFCS Levels II–IV), aged 4–10 years. Participants were randomly allocated into two groups: the intervention group received individualized NDT sessions five times per week for 12 weeks, while the control group received standard physical therapy. Gross Motor Function Measure-88 (GMFM-88) and Pediatric Evaluation of Disability Inventory (PEDI) mobility domain were used as outcome measures. Pre- and post-intervention scores were compared using paired and independent t-tests. A significance level of p < 0.05 was set.


Results: The intervention group showed a statistically significant improvement in GMFM-88 scores, with a mean change of 10.3 points (p = 0.0001), compared to 2.6 points (p = 0.08) in the control group. Similarly, PEDI mobility scores improved by 11.7 points (p = 0.0003) in the intervention group versus 2.1 points (p = 0.12) in the control group. Between-group comparisons confirmed the superiority of NDT in improving motor outcomes.


Conclusion: Neurodevelopmental therapy significantly enhances motor function and mobility in children with spastic cerebral palsy and should be considered a key component in pediatric rehabilitation strategies.

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How to Cite
1.
Sohu S, Sumera Makhdoom, Iqbal Ahmad Azhar, Sahaab Alvi, Duaa Joyo, Ayesha Khalid, et al. EFFECTIVENESS OF NEURODEVELOPMENTAL THERAPY ON MOTOR FUNCTION IMPROVEMENT IN CHILDREN WITH SPASTIC CEREBRAL PALSY. IJLSS [Internet]. 2025 Nov. 2 [cited 2025 Nov. 14];3(6 (Life):17-24. Available from: https://insightsjlss.com/index.php/home/article/view/397
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Author Biographies

Sohaila Sohu, Aga Khan University Hospital, Karachi, Pakistan.

Physical Therapist, Aga Khan University Hospital, Karachi, Pakistan.

Sumera Makhdoom, National Institute of Child Health (NICH), Karachi, Pakistan.

FCPS Postgraduate Trainee, National Institute of Child Health (NICH), Karachi, Pakistan.

Iqbal Ahmad Azhar, Azra Naheed Medical College, Lahore, Pakistan.

Professor and Head, Department of Pediatrics, Azra Naheed Medical College, Lahore, Pakistan.

Sahaab Alvi, Biosystomaics, Houston, Texas, USA.

Research Scientist, Biosystomaics, Houston, Texas, USA.

Duaa Joyo, University of Karachi, Karachi, Pakistan.

Research Associate, HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan.

Ayesha Khalid, Riphah International University, Islamabad, Pakistan.

Researcher, Riphah International University, Islamabad, Pakistan.

Abdul Aziz, Lifecare Hospital and Research Institute, Hayatabad, Peshawar, Pakistan.

Neurophysiology Technologist, Lifecare Hospital and Research Institute, Hayatabad, Peshawar, Pakistan.

How to Cite

1.
Sohu S, Sumera Makhdoom, Iqbal Ahmad Azhar, Sahaab Alvi, Duaa Joyo, Ayesha Khalid, et al. EFFECTIVENESS OF NEURODEVELOPMENTAL THERAPY ON MOTOR FUNCTION IMPROVEMENT IN CHILDREN WITH SPASTIC CEREBRAL PALSY. IJLSS [Internet]. 2025 Nov. 2 [cited 2025 Nov. 14];3(6 (Life):17-24. Available from: https://insightsjlss.com/index.php/home/article/view/397